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1

Synthesis and Anticancer Activity of 2-(Alkyl-, Alkaryl-, Aryl-, Hetaryl-)[1,2,4]triazolo[1,5-c]quinazolines

Kovalenko, Sergiy I.

Journal:

Scientia Pharmaceutica

Année:

2013

Langue:

english

Fichier:

PDF, 18.92 MB

english, 2013

2

ChemInform Abstract: Convenient Synthesis of Substituted 2-(2-Iminocoumarin-3-yl)thieno[2,3-d]pyrimidin-4-ones.

Pavlo E. Shynkarenko, Sergiy V. Vlasov, Sergiy M. Kovalenko, Svitlana V. Shishkina, Oleg V. Shishkin, Valentin P. Chernykh

Journal:

Année:

2010

Fichier:

PDF, 31 KB

2010

3

Convenient synthesis of substituted 2-(2-iminocoumarin-3-yl)thieno[2,3-d]pyrimidin-4-ones

Pavlo E. Shynkarenko, Sergiy V. Vlasov, Sergiy M. Kovalenko, Svitlana V. Shishkina, Oleg V. Shishkin, Valentin P. Chernykh

Journal:

Journal of Heterocyclic Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 185 KB

english, 2010

4

Multi-Component Reactions of Aldehydes, Amines, and Ketones I. Synthesis and Crystal Structure Elucidation of a Novel Product of Condensation of Salicylaldehyde, 1-Methyl-4-piperidone, and Methylamine

Sergiy M. Kovalenko, Valentyn P. Chernykh, Volodymyr M. Baumer, Svitlana S. Kovalenko

Journal:

Monatshefte für Chemie - Chemical Monthly

Année:

2002

Langue:

english

Fichier:

PDF, 88 KB

english, 2002

5

Synthesis of 5-Hydroxymethyl-8-methyl-3-(3-aryl-[1,2,4]oxadiazol-5-yl)-2 H -pyrano[2,3- c ]pyridin-2-ones and Their Esters

Zhuravel, Irina O., Kovalenko, Sergiy M., Zaremba, Oleg V., Detistov, Oleksandr S., Kovalenko, Svitlana S., Chernykh, Valentin P.

Journal:

Synthetic Communications

Année:

2008

Langue:

english

Fichier:

PDF, 164 KB

english, 2008

6

ChemInform Abstract: A Novel and Expedient Approach to New Heterocycles Containing Benzothiophene, Benzothieno[2,3-d]pyrmidine and Coumarin Moieties.

Yaroslav V. Bilokin, Maksym V. Vasylyev, Olena V. Branytska, Sergiy M. Kovalenko, Valentyn P. Chernykh

Journal:

Année:

2000

Fichier:

PDF, 31 KB

2000

7

Synthesis of Substituted Thienopyrimidine-4-ones.

Alexandre Ivachtchenko, Sergiy Kovalenko, Olena V. Tkachenko, Oleksiy Parkhomenko

Journal:

Année:

2004

Fichier:

PDF, 33 KB

2004

8

Synthesis of 5H-Pyrazolo[4,3-c]quinolines.

Olexiy V. Silin, Timur I. Savchenko, Sergiy M. Kovalenko, Viktor M. Nikitchenko, Alexandre V. Ivachtchenko

Journal:

Année:

2004

Fichier:

PDF, 13 KB

2004

9

Synthesis of Substituted 3-(5-Amino-[1,3,4]thiadiazol-2-yl)-2H-pyrano[2,3-c]pyridin-2-ones.

Irina O. Zhuravel, Sergiy M Kovalenko, Alexandre V. Ivachtchenko, Valentin P. Chernykh, Pavlo E. Shinkarenko

Journal:

Année:

2004

Fichier:

PDF, 18 KB

2004

10

Convenient Synthesis of Substituted 5-(Hydroxymethyl)-8-methyl-3-(4-phenylquinazolin-2-yl)-2H-pyrano [2,3-c]pyridin-2-ones.

Irina O. Zhuravel, Sergiy M. Kovalenko, Alexandre V. Ivachtchenko, Valentin P. Chernykh, Pavlo E. Shinkarenko

Journal:

Année:

2005

Fichier:

PDF, 17 KB

2005

11

ChemInform Abstract: Parallel Liquid-Phase Synthesis of 5-(1H-4-Pyrazolyl)-[1,2,4]oxadiazole Libraries.

Alexander V. Borisov, Oleksandr S. Detistov, Viktoria I. Pukhovaya, Irina O. Zhuravel, Sergiy M. Kovalenko

Journal:

Année:

2010

Fichier:

PDF, 50 KB

2010

12

ChemInform Abstract: Unexpected Alternative Direction of a Biginelli-Like Multicomponent Reaction with 3-Amino-1,2,4-triazole as the Urea Component.

Nikolay Yu. Gorobets, Yuriy V. Sedash, Konstantin S. Ostras, Oleg V. Zaremba, Svetlana V. Shishkina, Vyacheslav N. Baumer, Oleg V. Shishkin, Sergiy M. Kovalenko, Sergey M. Desenko, Erik V. Van der Eyc

Journal:

Année:

2010

Fichier:

PDF, 40 KB

2010

13

Synthesis of 5-methyl-4-oxo-2-(coumarin-3-yl)-N-aryl-3,4-dihydrothieno[2,3-d]-pyrimidine-6-carboxamides

Sergiy M. Kovalenko, Sergiy V. Vlasov, Valentin P. Chernykh

Journal:

Heteroatom Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 150 KB

english, 2007

14

Synthesis of substituted 3-(5-amino-[1,3,4]thiadiazol-2-yl)-2H-pyrano[2,3-c]pyridin-2-ones

Irina O. Zhuravel', Valentin P. Chernykh, Pavlo E. Shinkarenko, Sergiy M. Kovalenko, Alexandre V. Ivachtchenko

Journal:

Journal of Heterocyclic Chemistry

Année:

2004

Langue:

english

Fichier:

PDF, 222 KB

english, 2004

15

Synthesis and biological study of 3-(phenylsulfonyl)thieno[2,3-e][1,2,3]triazolo[1,5-a]pyrimidines as potent and selective serotonin 5-HT6 receptor antagonists

Alexandre V. Ivachtchenko, Elena S. Golovina, Madina G. Kadieva, Angela G. Koryakova, Sergiy M. Kovalenko, Oleg D. Mitkin, Ilya M. Okun, Irina M. Ravnyeyko, Sergey E. Tkachenko, Oleg V. Zaremba

Journal:

Bioorganic & Medicinal Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 511 KB

english, 2010

16

Unexpected alternative direction of a Biginelli-like multicomponent reaction with 3-amino-1,2,4-triazole as the urea component

Nikolay Yu. Gorobets, Yuriy V. Sedash, Konstantin S. Ostras, Oleg V. Zaremba, Svetlana V. Shishkina, Vyacheslav N. Baumer, Oleg V. Shishkin, Sergiy M. Kovalenko, Sergey M. Desenko, Erik V. Van der Eyc

Journal:

Tetrahedron Letters

Année:

2010

Langue:

english

Fichier:

PDF, 1017 KB

english, 2010

17

A novel and expedient approach to new heterocycles containing benzothiophene, benzothieno[2,3-d]pyrimidine and coumarin moieties

Yaroslav V. Bilokin, Maksym V. Vasylyev, Olena V. Branytska, Sergiy M. Kovalenko, Valentyn P. Chernykh

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 729 KB

english, 1999

18

Synthesis and antimicrobial activity of 5-hydroxymethyl- 8-methyl-2-(N-arylimino)-pyrano[2,3-c]pyridine-3-(N-aryl)-carboxamides

Irina O. Zhuravel’, Sergiy M. Kovalenko, Alexandre V. Ivachtchenko, Konstantin V. Balakin, Victor V. Kazmirchuk

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2005

Langue:

english

Fichier:

PDF, 119 KB

english, 2005

19

Solution Phase Parallel Synthesis of Substituted 3-Phenylsulfonyl-[1,2,3]triazolo[1,5-a]quinazolines: Selective Serotonin 5-HT6 Receptor Antagonists

Ivachtchenko, Alexandre V., Golovina, Elena S., Kadieva, Madina G., Koryakova, Angela G., Kovalenko, Sergiy M., Mitkin, Oleg D., Okun, Ilya M., Ravnyeyko, Irina M., Tkachenko, Sergey E., Zaremba, Oleg

Journal:

Journal of Combinatorial Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 854 KB

english, 2010

20

Synthesis and biological activity of novel N-cycloalkyl-(cycloalkylaryl)-2-[(3-R-2-oxo-2H-[1,2,4]triazino[2,3-c]quinazoline-6-yl)thio]acetamides

Galyna G. Berest, Olexii Yu. Voskoboynik, Sergiy I. Kovalenko, Olexii M. Antypenko, Inna S. Nosulenko, Andrii M. Katsev, Olena S. Shandrovskaya

Journal:

European Journal of Medicinal Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 329 KB

english, 2011

21

Synthesis of Substituted 4-Oxo-2-thioxo-1,2,3,4-tetrahydroquinazolines and 4-Oxo-3,4-dihydroquinazoline-2-thioles

Ivachtchenko, Alexandre V., Kovalenko, Sergiy M., Drushlyak, Oleksandr G.

Journal:

Journal of Combinatorial Chemistry

Année:

2003

Langue:

english

Fichier:

PDF, 601 KB

english, 2003

22

One-Pot Microwave-Assisted Synthesis of a Benzopyrano[2,3-c]pyrazol-3(2H)-one Library

Borisov, Alexander V., Gorobets, Nikolay Yu., Yermolayev, Sergey A., Zhuravel', Irina O., Kovalenko, Sergiy M., Desenko, Sergey M.

Journal:

Journal of Combinatorial Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 95 KB

english, 2007

23

Parallel Liquid-Phase Synthesis of 5-(1 H -4-Pyrazolyl)-[1,2,4]oxadiazole Libraries

Borisov, Alexander V., Detistov, Oleksandr S., Pukhovaya, Viktoria I., Zhuravel’, Irina O., Kovalenko, Sergiy M.

Journal:

Journal of Combinatorial Chemistry

Année:

2009

Langue:

english

Fichier:

PDF, 550 KB

english, 2009

24

The synthesis of low molecular weight pyrrolo[2,3-c]pyridine-7-one scaffold

Nechayev, Maxim A., Gorobets, Nikolay Yu., Borisov, Alexander V., Kovalenko, Sergiy M., Tolmachev, Andrey A.

Journal:

Molecular Diversity

Année:

2012

Langue:

english

Fichier:

PDF, 556 KB

english, 2012

25

Alkylation of 3‐Phenyl‐1 H ‐pyrazolo[4,3‐ c ] quinoline: Theoretical Analysis of Regioselectivity

Savchenko, Timur I., Silin, Olexiy V., Kovalenko, Sergiy M., Musatov, Vladymir I., Nikitchenko, Viktor M., Ivachtchenko, Alexander V.

Journal:

Synthetic Communications

Année:

2007

Langue:

english

Fichier:

PDF, 151 KB

english, 2007

26

Heat-Driven Release of a Drug Molecule from Carbon Nanotubes: A Molecular Dynamics Study

Chaban, Vitaly V., Savchenko, Timur I., Kovalenko, Sergiy M., Prezhdo, Oleg V.

Journal:

Journal of Physical Chemistry B

Année:

2010

Langue:

english

Fichier:

PDF, 2.43 MB

english, 2010

27

Parallel Liquid-Phase Synthesis of Benzopyrano[2,3- d ]pyrimidine Libraries

Borisov, Alexander V., Dzhavakhishvili, Sergey G., Zhuravel, Irina O., Kovalenko, Sergiy M., Nikitchenko, Victor M.

Journal:

Journal of Combinatorial Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 154 KB

english, 2007

28

SYNTHESIS OF NEW 3-SUBSTITUTED DERIVATIVES OF 7-AZACOUMARINES

Zhuravel, Irina Ο., Kovalenko, Svitlana S., Silin, Olexiy V., Kovalenko, Sergiy M.

Journal:

Heterocyclic Communications

Année:

2006

Langue:

english

Fichier:

PDF, 616 KB

english, 2006

29

Recyclization of 2-imino-2H-1-benzopyrans under the action of nucleophilic reagents: the novel approach for 2-(coumarin-3-yl)-3H-quinazolin-4-thiones

Kovalenko, Sergiy M., Vlasov, Sergiy V., Silin, Olexiy V., Chernykh, Valentin P.

Journal:

Journal of Sulfur Chemistry

Année:

2009

Langue:

english

Fichier:

PDF, 204 KB

english, 2009

30

Recyclization of 2-iminocoumarin-3-carbonitriles with 2-aminothiobenzamide: a new synthetic route to substituted 2-(2-iminocoumarin-3-yl)quinazoline-4(3 H )-thiones

Shynkarenko, Pavlo E., Vlasov, Sergiy V., Kovalenko, Sergiy M., Chernykh, Valentin P.

Journal:

Journal of Sulfur Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 162 KB

english, 2010

31

Hydrazinolysis of 3- R -[1,2,4]Triazino[2,3-c]quinazolin-2-ones. Synthetic and Theoretical Aspects

Sergeieva, Tetiana Yu., Voskoboynik, Oleksiy Yu., Okovytyy, Sergiy I., Kovalenko, Sergiy I., Shishkina, Svitlana V., Shishkin, Oleg V., Leszczynski, Jerzy

Journal:

Journal of Physical Chemistry A

Année:

2014

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2014

32

Synthesis of Substituted Thienopyrimidine-4-ones

Ivachtchenko, Alexandre, Kovalenko, Sergiy, Tkachenko, Olena V., Parkhomenko, Oleksiy

Journal:

Journal of Combinatorial Chemistry

Année:

2004

Langue:

english

Fichier:

PDF, 204 KB

english, 2004

33

Synthesis of 3‐Substituted 2‐Thioxo‐2,3‐dihydro‐1 H ‐benzofuro[3,2‐ d ] pyrimidin‐4(1 H )‐ones

Il'chenko, Olena V., Zaremba, Oleg V., Kovalenko, Sergiy M., Sherakov, Aliaksandr A., Chernykh, Valentin P.

Journal:

Synthetic Communications

Année:

2007

Langue:

english

Fichier:

PDF, 116 KB

english, 2007

34

Potential of N-aryl(benzyl,heteryl)-2-(tetrazolo[1,5-c]quinazolin-5-ylthio)acetamides as anticancer and antimicrobial agents

Antypenko, Oleksii M., Antypenko, Lyudmyla M., Kovalenko, Sergiy I., Katsev, Andrey M., Achkasova, Olena M.

Journal:

Arabian Journal of Chemistry

Année:

2014

Langue:

english

Fichier:

PDF, 920 KB

english, 2014

35

INVESTIGATION OF PLANT GROWTH REGULATION ACTIVITY OF ([1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-2-YLSULFANYL)CARBOXYLIC ACIDS AND AMIDESON CUCUMIS SATIVUS L. ROOTS

ANTYPENKO LYUDMYLA M.,KOVALENKO SERGIY I.,KORNET MARYNA M.

Journal:

Актуальні питання фармацевтичної і медичної науки та практики (Current issues in pharmacy and medicine science and practice)

Année:

2012

Langue:

english

Fichier:

PDF, 385 KB

english, 2012

36

Synthesis and electronic aspects of tetrahydrobenzothienopyrimidine derivatives

Gajda, Katarzyna, Astakhina, Valeriia, Ejsmont, Krzysztof, Kolomeitsev, Dmytro, Kovalenko, Sergiy, Zarychta, Bartosz

Journal:

Journal of Molecular Structure

Année:

2015

Langue:

english

Fichier:

PDF, 1.41 MB

english, 2015

37

Convenient Synthesis of Substituted 5‐(Hydroxymethyl)‐8‐methyl‐3‐(4‐phenylquinazolin‐2‐yl)‐2 H ‐pyrano[2,3‐ c ]pyridin‐2‐ones

Zhuravel, Irina O., Kovalenko, Sergiy M., Ivachtchenko, Alexandre V., Chernykh, Valentin P., Shinkarenko, Pavlo E.

Journal:

Synthetic Communications

Année:

2005

Langue:

english

Fichier:

PDF, 152 KB

english, 2005

38

Microwave-assisted acid-catalyzed nucleophilic heteroaromatic substitution: the synthesis of 7-amino-6-azaindoles

Nechayev, Maxim A., Gorobets, Nikolay Yu., Shishkina, Svetlana V., Shishkin, Oleg V., Kovalenko, Sergiy M.

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 4.52 MB

english, 2015

39

Atomistic Simulations of Coating of Silver Nanoparticles with Poly(vinylpyrrolidone) Oligomers: Effect of Oligomer Chain Length

Kyrychenko, Alexander, Korsun, Oleksandr M., Gubin, Iurii I., Kovalenko, Sergiy M., Kalugin, Oleg N.

Journal:

The Journal of Physical Chemistry C

Année:

2015

Langue:

english

Fichier:

PDF, 2.01 MB

english, 2015

40

2-Alkyl(aryl)-quinazolin-4(3 H )-thiones, 2-R-(quinazolin-4(3 H )-ylthio)carboxylic acids and amides: synthesis, molecular docking, antimicrobial and anticancer properties

Antypenko, Lyudmyla, Kovalenko, Sergiy, Posylkina, Yulia, Nikitin, Vladyslav, Fedyunina, Natalia, Ivchuk, Vitalii

Journal:

Journal of Enzyme Inhibition and Medicinal Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 743 KB

english, 2015

41

SOLUTION AND SOLID-PHASE APPROACHES TO QUINCONAZOLE AND FLUQUINCONAZOLE - INHIBITORS OF FUNGAL ERGOSTEROL BIOSYNTHESIS

Bilokin, Yaroslav V., Kovalenko, Sergiy M.

Journal:

Heterocyclic Communications

Année:

2000

Langue:

english

Fichier:

PDF, 1.10 MB

english, 2000

42

SPECIFIC FEATURES OF REACTIONS OF 2-AMINOBENZOTRIFLUORIDE AND ANTHRANILATES WITH ETHYL CYANOACETATE — EXPEDITIOUS ROUTES TO 3-SUBSTITUTED 4-AMINO- AND 4-HYDROXYQUINOLIN-2(1 H)-ONES

Bylov, Igor E., Bilokin, Yaroslav V., Kovalenko, Sergiy M.

Journal:

Heterocyclic Communications

Année:

1999

Langue:

english

Fichier:

PDF, 648 KB

english, 1999

43

A FACILE METHOD FOR SYNTHESIS OF HETEROCYCLES CONTAINING TETRAHYDROBENZO[4,5]THIENO[2,3-d]PYRIMIDINE AND COUMARIN MOIETIES

Vasylyev, Maxym V., Bilokin, Yaroslav V., Branytska, Olena V., Kovalenko, Sergiy M., Chernykh, Valentyn P.

Journal:

Heterocyclic Communications

Année:

1999

Langue:

english

Fichier:

PDF, 350 KB

english, 1999

44

SYNTHESIS OF 3-ARYL-5-R-THIO-[1,3]THIAZOLO[4',5':4,5]PYRIMIDO-[1,6-a] BENZIMIDAZOLE-2(3H)-THIONES

Ivachtchenko, Alexandre, Kovalenko, Sergiy, Parkhomenko, Olexiy, Chernykh, Valentyn

Journal:

Heterocyclic Communications

Année:

2002

Langue:

english

Fichier:

PDF, 282 KB

english, 2002

45

2-Heteroaryl-[1,2,4]triazolo[1,5- c ]quinazoline-5(6 H)-thiones and Their S-Substituted Derivatives: Synthesis, Spectroscopic Data, and Biological Activity

Bilyi, Andrii K., Antypenko, Lyudmyla M., Ivchuk, Vitalii V., Kamyshnyi, Oleksandr M., Polishchuk, Natalya M., Kovalenko, Sergiy I.

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 1.93 MB

english, 2015

46

SYNTHESIS OF BENZIMIDAZO[1,2-c]QUINAZOLINE-6(5H)-THIONES

Ivachtchenko, Alexandre, Kovalenko, Sergiy, Drushlyak, Oleksandr

Journal:

Heterocyclic Communications

Année:

2002

Langue:

english

Fichier:

PDF, 612 KB

english, 2002

47

Hematopoietic cell infusion for the treatment of nuclear disaster victims: New data from the Chernobyl accident

Klymenko, Sergiy V., Belyi, David A., Ross, Joel R., Owzar, Kouros, Jiang, Chen, Li, Zhiguo, N. Minchenko, Janna, N. Kovalenko, Aleksandr, Bebeshko, Volodymyr G., J. Chao, Nelson

Journal:

International Journal of Radiation Biology

Année:

2011

Langue:

english

Fichier:

PDF, 630 KB

english, 2011

48

An Efficient Synthesis of 1,3,7-Triazaspiro[4.4]Nonane-2,4-Dione Derivatives and Antimicrobial Activity Thereof

Krolenko, Konstantin Yu., Silin, Olexiy V., Vlasov, Sergiy V., Zhuravel, Irina O., Kovalenko, Sergiy M.

Journal:

Chemistry of Heterocyclic Compounds

Année:

2015

Langue:

english

Fichier:

PDF, 231 KB

english, 2015

49

Formation of 1-methyl[1,2,4]triazolo[4,3-a] quinazolin-5(4H)-ones by reaction of 2-hydrazinoquinazolin-4(3H)-ones with acetylacetone

Danylchenko, Svitlana Yuriyivna, Drushlyak, Oleksandr Grygorovych, Kovalenko, Svitlana Sergiyivna, Kovalenko, Sergiy Mykolayovych

Journal:

Heterocyclic Communications

Année:

2015

Langue:

english

Fichier:

PDF, 450 KB

english, 2015

50

Recyclization of 2-Imino-2 H -1-benzopyrans with Nucleophilic Reagents - Reaction of 2-Iminocoumarin-3-carboxamides with 2-Aminothiophene-3-carboxamides

Kovalenko, Sergiy M., Vlasov, Sergiy V., Chernykh, Valentin P.

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 94 KB

english, 2006